The authors declare that have no competing interest related to this
manuscript. This study was supported by a research grant from the French
Agency for Food, Environmental and Occupational Health & Safety
All authors were part of the working group and contributed to the literature
research, the analyse of the literature and the interpretation of the results.
OB was head of the working group and drafted the manuscript. All authors
read and approved the final manuscript.
The present review is based on the opinion of the French Agency for Food,
Environmental and Occupational Health & Safety on the assessment of the
nutritional benefits and risks related to intense sweeteners.
The opinion and the full expert report are available on Anses’ website:
The authors thank Veronique Rabenda and Delphine Nicolet for their
valuable help with the bibliographic research.
1Department of Public Health, Epidemiology and Health Economics,
University of Liege, CHU Sart Tilman, Bât B23, 4000, Liège, Belgium. 2CNRS
UMR 5293/Université de Bordeaux, Bordeaux, France. 3Centre Hospitalier de
Luxembourg, Luxembourg, Luxembourg. 4Université de Picardie, Amiens,
France. 5Centre Hospitalier Universitaire Vaudois, Lausanne, Suisse,
Switzerland. 6Centre des Sciences du Goût et de l’Alimentation – INRA Dijon,
Dijon, France. 7Université Claude Bernard Lyon 1, Hospices Civils de Lyon,
Inserm U1060, Lyon, France. 8Sorbonne Universités, UPMC Univ Paris 06,
Paris, France. 9French Agency for Food, Environmental and Occupational
Health & Safety (Anses), Maisons-Alfort, France. 10INSERM 855/Université
Claude Bernard Lyon 1, Lyon, France. 11Hôtel-Dieu Hospital, René Descartes
University-Paris V, Paris, France.
Received: 23 March 2015 Accepted: 26 August 2015